11 scientific methods to help slow down the aging process and increase longevity

Aging is no longer a concern of only women, but has become a concern of everyone. Some people try everything to slow down this natural process. If you are one of them, you can feel safe now. Scientists have studied and found a number of methods that can help us prolong our youth and slow down the aging process.

Join Hello Bacsi to learn more about ways to slow down the aging process with the help of modern science and technology!

1. Remove aging cells

A team of scientists from the Mayo Clinic, USA, conducted studies in mice to find out the effects of anti-aging drugs (also called longevity therapies or senolytics). They found that the drug eliminated senescent cells, was able to prevent cell damage, restore physical function and prolong the lives of aged mice.

Meanwhile, last year, Unity Biotechnology, USA, launched the first human clinical trials to test this anti-aging therapy. Their goal is to cure knee arthritis, a disease closely linked with cellular aging in the joints.

2. Gene mutation

Have you ever wondered why some mammals live so long? Researchers from the UK and Spain have been trying to find an answer to this question. They linked specific genomes to those of long-lived primates using bioinformatics. It is a field of science that uses the technologies of applied mathematics, informatics, statistics, computer science, artificial intelligence, chemistry, and biochemistry to solve biological problems.

They discovered 25 genetic mutations that are involved in wound healing, blood clotting and cardiovascular treatment. Now, they want to use these results to study the aging process in humans.

3. Biomarkers of aging

A biomarker is an indicator that measures the severity or presence of certain disease states. Biomarkers can be as simple as chemicals, like glucose as a marker for diabetes, or a gene or DNA marker as a marker for genetic diseases.

Steve Horvath, a bioinformatics expert, worked to generate reliable features of biological age. Last year, Horvath and a team of researchers developed a new biomarker of aging they called DNAm PhenoAge. It is much better than previous biomarkers and can predict various outcomes of aging, including mortality from cancer or Alzheimer’s.

4. Stem cell therapy against cancer and diabetes

The researchers were able to store certain stem cells and were able to stimulate these cells to develop into appropriate organs. Stem cells are stored at low temperature. When needed, these cells will be used to regenerate cells and tissues.

One of the start-ups (startups) launched in 2018 was involved in the development of this type of therapy using placental stem cells to treat diseases such as cancer, Crohn’s disease, diabetes. Street…

5. Soften wrinkles in the cell nucleus

As we age, we are often only concerned with the wrinkles on our faces. However, there is a problem that needs more attention than that is wrinkles in the cell nucleus.

In 2018, researchers from the University of Virginia, USA, found that most aging agents, such as fatty liver disease, can result from the appearance of wrinkles in the cell nucleus, causing The nucleus becomes curved and wrinkled. The fact that those wrinkles appear has a bad effect on the gene’s activity, causing it to go wrong.

According to their studies, the virus can be modified to deliver lamin (intermediate filament) to human cells. Lamin is a fibrous protein that provides structural functions and regulates transcription in the cell nucleus, which in turn can soften and smooth cell wrinkles.

6. 3D printing human tissue with capillaries

In June 2018, Prellis Biologics announced that they could print tissues with living human capillaries. Printed tissues can be used for transplantation. This advancement will make it possible to print vital organs and replace them for old, diseased or deformed parts. This will greatly reduce the number of deaths due to the lack of organs for transplantation.

Recently, Israeli scientists have successfully used a 3D bioprinter to create a heart complete with tissue and blood vessels similar to a human heart, not only opening up new prospects for patients who need a heart transplant but for patients in need of other organ transplants.

7. Transgenic

Over the past few years, researchers have made great achievements in the treatment and prevention of diseases by eliminating aging cells or those that have stopped dividing. The scientists used transgenic methods and conducted initial experiments on mice.

In 2018, two independent research groups used a transgenic approach to prevent neurodegeneration. Following those results, scientists from the Mayo Clinic conducted a study on how to remove aging brain cells in patients with Alzheimer’s disease, preventing brain degeneration.

Another lab used genetic engineering to destroy old cells in the brains of mice exposed to the herbicide, which is a major cause of Parkinson’s disease in humans and mice. The results of the study show that this gene therapy has positive signs in the treatment of Parkinson’s disease in mice.

8. Blood transfusion against memory loss

In one experiment, it was found that blood transfusion from young mice to old mice stimulated neurons and stem cells in the brains of old mice. This can completely reverse the effects of the aging process. This is also the start-up project called Ambrosia, which allows patients to pay $ 8,000 to buy plasma from young people.

Although the results of the trial were not clear and there were many objections to the Ambrosia project, a clinical study was still underway. The results obtained from this study were surprising. Biomarkers of older people with Alzheimer’s disease and cardiovascular problems showed significant improvement. Unfortunately, in some patients, however, this effect does not last long.

9. Mental health

Psychological disorders (or mental disorders), including substance abuse, can accelerate the aging process. A study published in August 2018 analyzed more than 60,000 brain scans of people aged 9 months to 105 years. A team of researchers, including scientists from Google and Johns Hopkins University, USA, found that the cause of premature aging is due to:

• Schizophrenia (on average, 4 years reduction in life expectancy)
• Marijuana abuse (2.5 years)
• Bipolar disorder (1.6 years)
• Attention Deficit Hyperactivity Disorder (1.4 years)
• Alcohol abuse (0.6 years)

In addition, they also found that depression had nothing to do with accelerated aging.

10. Diet

Scientists have proven that reducing calorie consumption can actually slow down the aging process and reduce the risk of aging-related diseases. A study conducted in 2018 found that the timing and amount of food you eat has anti-aging effects and reduces the risk of diseases such as cardiovascular disease, diabetes, cancer and dementia. Scientists recommend that you follow an “intermittent fasting” diet.

11. Lifestyle

We hear every day about the benefits of eating right, exercising, and avoiding bad habits. In 2018, it was proven that these things can actually help extend your life by 10 years.

A 34-year study showed that if people quit smoking, keep their body mass index (BMI) between 18.5 and 24.9, exercise for 30 minutes a day, reduce alcohol intake. By consuming and following a healthy diet, men can extend their life expectancy by 12 years and women by 14 years.

Aging has become a concern for many people. Fortunately, scientists around the world have been working to find ways to “reverse aging” and increase life expectancy.

However, the most practical way to protect yourself against the “power of time” is to maintain a healthy lifestyle and follow a sensible diet. Do not wait for the intervention of science and technology, you can also “fight” and win with aging from now on. Hopefully, Hello Bacsi has provided you with the necessary information on how to slow down aging and increase human longevity thanks to science and technology.

Phuong Quynh/HELLO BACSI